Location History:
- Brookline, MA (US) (2012 - 2015)
- Miami, FL (US) (2014 - 2022)
Company Filing History:
5 out of 315 
5 out of 1,386 
4 out of 377 
Years Active: 2012-2022
Title: The Innovative Contributions of Tan A Ince
Introduction
Tan A Ince is a prominent inventor based in Brookline, MA, known for his significant contributions to the field of biomedical research. With a total of nine patents to his name, Ince has made remarkable advancements in tissue culture systems and cancer research. His work has the potential to transform the understanding and treatment of various diseases.
Latest Patents
Among his latest patents, Ince developed a hormone-responsive tissue culture system that provides a unique environment for primary cells, particularly normal mammalian primary epithelial progenitors. This innovative system includes a serum-free, chemically defined cell culture media and methods for the isolation and long-term propagation of primary cells. The cells cultured using this system can remain undifferentiated and proliferate for extended periods without senescence or genetic alterations. Furthermore, upon altering the culture conditions, these cells can be induced to differentiate, showcasing their versatility.
Ince's other notable patent involves a specialized cell culture medium for breast cancer cells. This medium comprises various essential components, including adenosine triphosphate, carrier proteins, and several vitamins and minerals, while being substantially free of certain hormones and ligands. This formulation aims to enhance the growth and study of breast cancer cells, providing valuable insights into cancer biology.
Career Highlights
Throughout his career, Tan A Ince has worked with esteemed institutions such as the Whitehead Institute for Biomedical Research and Brigham and Women's Hospital, Inc. His research has significantly impacted the field of cancer research, particularly in understanding the behavior of cancer stem cells and their role in tumor development.
Collaborations
Ince has collaborated with notable figures in the field, including Robert Allan Weinberg and Sandro Santagata. These partnerships have further enriched his research and contributed to the advancement of knowledge in cancer biology.
Conclusion
Tan A Ince's innovative work in tissue culture systems and cancer research highlights his role as a leading inventor in the biomedical field. His contributions continue to pave the way for new treatments and a deeper understanding of complex diseases.