This inventor holds 5 USPTO granted patents. Top assignee: Kitasato Kenkyusho. Active years: 1987-1993.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Chiba, JP (1987 - 1993)
- Ichikawa, JP (1988 - 1993)
Company Filing History:
Years Active: 1987-1993
Title: Innovations in Dental Health: The Contributions of Takashi Tsurumizu
Introduction
Takashi Tsurumizu is a notable inventor based in Ichikawa, Japan. He has made significant contributions to the field of dental health through his innovative research and patents. With a total of 5 patents, Tsurumizu's work focuses on developing non-cariogenic vaccines and compositions aimed at preventing dental caries.
Latest Patents
One of Tsurumizu's latest patents involves the development of vaccines, antibodies, and antibody-containing compositions that inhibit PLS antigens I and II. These antigens are derived from the pili-like structures on the cell wall of Human type Streptococcus mutans. They are capable of specifically inhibiting the adherence of corresponding strains to human teeth. The antigens consist of glycoproteins, comprising approximately 15-25% protein and 75-85% carbohydrates, with a molecular weight ranging from 60,000 to 90,000. The isolation of these antigens is achieved by extracting intact cells in a hypertonic buffer solution at a pH of 6-8 and at a temperature below the denaturing point of the antigenic protein. Tsurumizu's non-cariogenic vaccine comprises PLS antigens I and/or II, and non-cariogenic antibodies can be produced by immunizing mammals with these antigens. The resulting antibodies can be recovered and formulated into compositions suitable for oral administration, such as dentifrices, gargles, and even ice creams.
Career Highlights
Takashi Tsurumizu is associated with Kitasato Kenkyusho, where he continues to advance his research in dental health. His work has garnered attention for its potential to revolutionize how dental caries are prevented and treated.
Collaborations
Tsurumizu collaborates with notable colleagues, including Takashi Hashimoto and Makoto Sato. Their combined expertise contributes to the innovative research being conducted at Kitasato Kenkyusho.
Conclusion
Takashi Tsurumizu's contributions to dental health through his innovative patents highlight the importance of research in preventing dental caries. His work not only showcases his dedication to improving oral health but also emphasizes the potential for future advancements in this critical field.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile