Company Filing History:
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Years Active: 1999-2013
Title: The Innovations of Takao Koike
Introduction
Takao Koike is a notable inventor based in Sapporo, Japan. He has made significant contributions to the field of medical diagnostics, particularly in the detection of leukemia and blood coagulation assays. With a total of 4 patents to his name, his work has the potential to greatly impact patient care and treatment outcomes.
Latest Patents
One of Koike's latest patents is a method of detecting leukemic cells. This innovative approach provides a marker that is useful in diagnosing leukemia. The method involves detecting a CD34-positive cell that is negative in DOCK180 expression from a blood specimen. This technique confirms a DOCK180 expression pattern specific to tumor cells in leukemia, especially acute leukemia. It allows doctors to obtain valuable information for diagnosing and monitoring the severity and recovery of the disease through a convenient blood specimen procedure.
Another significant patent is related to the assay of lupus anticoagulant and the corresponding assay reagent. This invention includes a monoclonal antibody that has inhibitory activity on blood coagulation reactions. It reacts with prothrombin when forming a complex with phosphatidylserine but does not react with prothrombin that is not forming such a complex. The method for measuring the inhibitory activity of test plasma on blood coagulation reactions involves comparing the test plasma's inhibitory activity with that of the antibody.
Career Highlights
Throughout his career, Takao Koike has worked with reputable organizations such as Yamasa Corporation and Hokkaido University. His experience in these institutions has contributed to his expertise in medical research and innovation.
Collaborations
Koike has collaborated with notable colleagues, including Eiji Matsuura and Tomoyoshi Katahira. Their joint efforts have likely enhanced the quality and impact of his research.
Conclusion
Takao Koike's contributions to medical diagnostics through his innovative patents demonstrate his commitment to improving healthcare. His work in detecting leukemia and blood coagulation assays showcases the importance of research and innovation in medicine.