Takahashi Masaaki

Title: Takahashi Masaaki: Innovator in Neurobiology

Introduction

Takahashi Masaaki is a prominent inventor based in Baltimore, MD (US). He has made significant contributions to the field of neurobiology, particularly through his research on serine racemase. His work has implications for understanding and treating various neurological conditions.

Latest Patents

Takahashi holds a patent for his invention titled "Mammalian serine racemase." This patent describes the enzyme that catalyzes the direct racemization of L-serine to D-serine, which is crucial in the mammalian brain. The enzyme has a molecular weight of 37 kDa and requires pyridoxal 5'-phosphate for its activity. It is highly selective toward L-serine and does not racemize any other amino acid tested. His research also includes identifying polynucleotide sequences that encode mammalian serine racemase, including that of humans. The compounds that modulate the activity of this enzyme are useful for treating conditions involving overstimulation of NMDA receptors, such as stroke and various neurodegenerative diseases.

Career Highlights

Takahashi Masaaki is affiliated with The Johns Hopkins University, where he conducts his research. His work has garnered attention for its potential applications in medical science and therapeutic interventions.

Collaborations

He has collaborated with notable colleagues, including Soloman H Snyder and Herman Wolosker, who have contributed to the advancement of research in this area.

Conclusion

Takahashi Masaaki's innovative work in neurobiology, particularly regarding serine racemase, highlights the importance of his contributions to medical science. His research continues to pave the way for new treatments for neurological disorders.