Company Filing History:
Years Active: 1999-2004
Title: Swati R Mujumdar: Innovator in Fluorescent Labeling Complexes
Introduction
Swati R Mujumdar is a prominent inventor based in Glenshaw, PA (US). She has made significant contributions to the field of fluorescent labeling complexes, holding a total of five patents. Her work focuses on developing innovative solutions for multiparameter fluorescence cell analysis.
Latest Patents
One of her latest patents involves the creation of fluorescent labeling complexes with large Stokes shifts formed by coupling cyanine and other fluorochromes capable of resonance energy transfer. This invention provides low molecular weight fluorescent labeling complexes that exhibit substantial wavelength shifts between the absorption of one dye and the emission from another. These complexes are particularly useful for multiparameter fluorescence cell analysis using a single excitation wavelength. The low molecular weight allows materials labeled with the complex to penetrate cell structures effectively, making them suitable for use as probes. The synthesis of these labeling complexes involves covalently attaching at least one cyanine fluorochrome to another low molecular weight fluorochrome through linkers, forming energy donor-acceptor complexes. The resonance energy transfer from an excited donor to a fluorescent acceptor can achieve wavelength shifts of up to 300 nm. Additionally, the complexes are designed to contain reactive groups for labeling functional groups on target compounds, including derivatized oxy and deoxy polynucleic acids, antibodies, enzymes, and proteins.
Career Highlights
Swati R Mujumdar is affiliated with Carnegie Mellon University, where she continues her research and development in the field of fluorescent labeling technologies. Her innovative work has positioned her as a key figure in advancing scientific understanding and applications of fluorescence in various research areas.
Collaborations
Some of her notable coworkers include Alan S Waggoner and Ratnakar B Mujumdar, who have collaborated with her on various projects related to her patents and research initiatives.
Conclusion
Swati R Mujumdar's contributions to the field of fluorescent labeling complexes demonstrate her commitment to innovation and scientific advancement. Her patents reflect her expertise and the potential impact of her work on future research and applications in cell analysis.