Company Filing History:
Years Active: 2014-2018
Title: Susan Wigdal: Innovator in Biosensor Technology
Introduction
Susan Wigdal is a prominent inventor based in Belleville, WI (US), known for her significant contributions to the field of biosensor technology. With a total of 7 patents to her name, she has made remarkable advancements in the development of luciferase proteins that serve as sensors for various molecules.
Latest Patents
Among her latest patents is the development of permuted and nonpermuted luciferase biosensors. This innovation involves a modified luciferase protein that acts as a sensor for molecules such as cAMP, cGMP, calcium, and various kinases or phosphatases. Additionally, she has introduced a circularly permuted anthozoan luciferase protein and a decapod crustacean luciferase protein, which may contain heterologous amino acid sequences that interact with target molecules. Another notable patent focuses on mutant protease biosensors with enhanced detection characteristics. This invention features a polynucleotide encoding a biosensor polypeptide that includes a modified circularly-permuted thermostable luciferase linked to a sensor region capable of interacting with target molecules in cells.
Career Highlights
Susan Wigdal is currently employed at Promega Corporation, where she continues to push the boundaries of biosensor technology. Her work has been instrumental in advancing the capabilities of luciferase proteins, making them more effective for scientific research and applications.
Collaborations
Throughout her career, Susan has collaborated with notable colleagues, including Brock Binkowski and Frank Fan. These partnerships have contributed to her innovative research and the successful development of her patented technologies.
Conclusion
Susan Wigdal's contributions to biosensor technology exemplify her dedication to innovation and scientific advancement. Her work continues to impact the field significantly, showcasing the importance of her inventions in modern research.
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