Susan Vandewoude

Title: Susan Vandewoude: Innovator in Borna Disease Research

Introduction

Susan Vandewoude is a prominent inventor based in Loveland, CO (US). She has made significant contributions to the field of virology, particularly in understanding the Borna disease virus (BDV). With a total of 3 patents to her name, her work has implications for both animal health and virology research.

Latest Patents

One of her latest patents focuses on Borna disease virus-specific DNA and proteins. The Borna disease virus is known to cause a rare neurological disease in horses and sheep. In her research, a subtractive cDNA expression library was constructed using poly A-selected RNA from a BDV-infected MDCK cell line. A specific clone (B8) was isolated that hybridizes to RNA from BDV-infected brain tissue and cell lines. This clone interacts with four BDV-specific positive strand RNAs and one negative strand RNA found in BDV-infected rat brain. Nucleotide sequence analysis indicates that this clone represents a full-length mRNA containing several open reading frames. The patent provides valuable insights into the DNA sequences and proteins encoded by the BDV DNA sequences.

Career Highlights

Susan Vandewoude is affiliated with Johns Hopkins University, where she continues her research in virology. Her work has been instrumental in advancing the understanding of BDV and its effects on neurological health in animals.

Collaborations

Some of her notable coworkers include Janice E Clements and Opendra Narayan, who have collaborated with her on various research projects.

Conclusion

Susan Vandewoude's innovative research on the Borna disease virus has led to significant advancements in the field of virology. Her contributions are vital for understanding and combating neurological diseases in animals.