Company Filing History:
Years Active: 1998-2000
Title: Innovations by Susan M Maciukas
Introduction
Susan M Maciukas is a notable inventor based in El Cerrito, California. She has made significant contributions to the field of hematology through her innovative inventions. With a total of 3 patents, her work focuses on serum-free suspensions of human hematopoietic cells and methods for treating neutropenia.
Latest Patents
One of her latest patents involves the preparation of serum-free, animal protein-free media formulations. These formulations are designed to be used in conjunction with hematopoietic growth factors for the in vitro growth of human neutrophil and megakaryocyte precursors. The medium contains a base medium, corticosteroid, transferrin, insulin, cholesterol, ethanolamine, and human albumin. Additionally, she has developed methods for preparing serum-free, animal protein-free suspensions of human hematopoietic precursor cells. These suspensions contain at least about 16% neutrophil precursors and at least about 1% megakaryocyte precursors. Furthermore, her inventions provide serum-free, animal protein-free suspensions wherein the cellular component comprises at least about 30% neutrophil precursors.
Another significant patent addresses the infusion of neutrophil precursors for the treatment of neutropenia. This invention provides a method for treating patients with a reduced population of neutrophils following myeloablative cancer treatments, such as high-dose chemotherapy. The method involves administering a cell composition of at least 25% neutrophil precursors to the patient, allowing for rapid differentiation in vivo to replenish the supply of mature neutrophils.
Career Highlights
Susan M Maciukas is currently associated with Nexell Therapeutics Inc., where she continues to innovate in the field of hematology. Her work has been instrumental in advancing treatments for patients undergoing cancer therapies.
Collaborations
Some of her notable coworkers include Stephen L Smith and Xiaoying Qiao, who contribute to her research and development efforts.
Conclusion
Susan M Maciukas is a pioneering inventor whose work in hematology has led to significant advancements in the treatment of neutropenia and the development of serum-free cell suspensions. Her contributions continue to impact the medical field positively.