This inventor holds 4 USPTO granted patents and 2 published patent applications. Top assignees: Moleculera Labs, Inc., The United States of America as Represented by the Department of Health, The United States of America, as Represented by the Secretary, Department of Health and Human Services. Active years: 1991-2019.
Location History:
- Lorton, VA (US) (1991)
- McLean, VA (US) (1999 - 2019)
Company Filing History:
2 out of 2 
2 out of 1,217 
2 out of 3,688 
Years Active: 1991-2019
Title: Susan E. Swedo: Innovator in Pediatric Neuropsychiatric Disorders
Introduction
Susan E. Swedo is a prominent inventor based in McLean, VA (US). She has made significant contributions to the field of pediatric neuropsychiatric disorders, holding a total of 4 patents. Her work focuses on developing diagnostic methods that can greatly impact the treatment of children suffering from these conditions.
Latest Patents
One of her latest patents is a diagnostic method for pediatric acute-onset neuropsychiatric syndrome (PANS) and pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection (PANDAS). This invention provides a panel of at least five clinical analyses or tests using serum samples to determine the risk of PANS and/or PANDAS in an individual. The method includes enzyme-linked immunosorbent assays (ELISAs) to measure antibody titers against neuronal antigens present in the brain. The neuronal antigens include lysoganglioside, tubulin, dopamine receptor D1, dopamine receptor D2, serotonin receptor 5HT2A, and serotonin receptor 5HT2C. Antibody titers against at least four of these neuronal antigens are required in the present methods, with a preference for measuring all of them. A final assay quantifies calcium/calmodulin-dependent protein kinase activity using a neuronal cell line. The results of these analyses are combined using an algorithm to determine whether a PANS or PANDAS diagnosis is appropriate for the individual. Depending on the diagnosis, an appropriate treatment can then be determined.
Career Highlights
Throughout her career, Susan has worked with notable organizations, including the United States of America as represented by the Department of Health and Moleculera Labs, Inc. Her innovative approaches have paved the way for better understanding and treatment of pediatric neuropsychiatric disorders.
Collaborations
Susan has collaborated with esteemed colleagues such as Christine Kirvan and Craig David Shimasaki. These partnerships have further enhanced her research and contributions to the field.
Conclusion
Susan E. Swedo's work in developing diagnostic methods for pediatric neuropsychiatric disorders has made a significant impact on the medical community. Her innovative patents and collaborations continue to advance the understanding and treatment of these complex conditions.