Sunita Khanderao Gadakh

Title: Sunita Khanderao Gadakh: Innovator in Synthetic Chemistry

Introduction

Sunita Khanderao Gadakh is a prominent inventor based in Maharashtra, India. She has made significant contributions to the field of synthetic chemistry, particularly in the development of novel synthetic routes for pharmaceutical compounds. Her work is crucial in the fight against HIV, showcasing her dedication to advancing medical science.

Latest Patents

Sunita holds a patent for a process titled "Process for synthesis of syn azido epoxide and its use as intermediate for the synthesis of amprenavir and saquinavir." This innovative synthetic route involves cobalt-catalyzed hydrolytic kinetic resolution of a racemic mixture of the azido-epoxide. The reaction steps include epoxidation of an allylic alcohol, ring opening with azide anion, selective tosylation, and further treatment to obtain the syn-azido epoxide. This compound serves as a common intermediate for the asymmetric synthesis of HIV protease inhibitors, including Amprenavir, Fosamprenavir, Saquinavir, and formal synthesis of Darunavir and Palinavir. Sunita has 1 patent to her name.

Career Highlights

Sunita is affiliated with the Council of Scientific and Industrial Research, where she continues to engage in groundbreaking research. Her work not only contributes to scientific knowledge but also has practical applications in the pharmaceutical industry.

Collaborations

Sunita has collaborated with notable colleagues, including Reddy Santhosh Rekula and Arumugam Sudalai. These partnerships enhance her research capabilities and foster innovation in her field.

Conclusion

Sunita Khanderao Gadakh exemplifies the spirit of innovation in synthetic chemistry. Her contributions to the development of HIV protease inhibitors highlight her importance in the scientific community. Her work continues to inspire future generations of inventors and researchers.