Company Filing History:
Years Active: 2012-2013
Title: Innovator in Nucleic Acid Engineering - Sunil S. Chandran
Introduction
Sunil S. Chandran, based in Emeryville, California, is a notable inventor recognized for his contributions to the field of nucleic acid assembly and engineering. With a portfolio of four patents, Chandran has made significant strides in developing methods and compositions that enhance the efficiency and accuracy of polynucleotide assembly, which is crucial for advancements in genetic engineering and biotechnology.
Latest Patents
Chandran’s most recent patents include:
1. **Compositions and Methods for the Assembly of Polynucleotides**: This invention provides innovative compositions and methods for the rapid assembly of assembled polynucleotides. Utilizing circular nucleic acid vectors, the invention aims to streamline the process of generating DNA fragments through restriction endonuclease digestion. The method employs annealable linker sequences, which facilitate host cell-mediated homologous recombination or polymerase cycling assembly, thus enabling the ordered assembly of various DNA segments into one or more polynucleotides.
2. **Systems and Methods for Engineering Nucleic Acid Constructs Using Scoring Techniques**: This patent outlines systems and methods for defining nucleic acid constructs for integration within a specific locus of an organism. It involves receiving genetic change requests, expanding them into component polynucleotides, and scoring different arrangements to select the optimal nucleic acid construct for amplification. This meticulous engineering process is pivotal in genetic modification and biotechnology applications.
Career Highlights
Throughout his career, Sunil S. Chandran has played a vital role at various research institutions and biotechnology companies. Notably, he has contributed to the innovations at Amyris, Inc. and Amyris Biotechnologies, Inc. His work has significantly impacted the development of nucleic acid technologies and has positioned him as a key figure in the field.
Collaborations
Chandran has collaborated with esteemed colleagues such as Zach Serber and Raymond Lowe, further enhancing the collaborative environment that fuels innovation in biotechnology and genetic research. Together, they have worked on advancing methods that are essential for the precise manipulation of genetic material.
Conclusion
Sunil S. Chandran stands out as an influential inventor in the realm of nucleic acid engineering. With his four patents, he has made notable advancements that pave the way for the future of genetic engineering. Through his innovative methods and collaborative spirit, Chandran continues to push the boundaries of biotechnology, offering solutions that are vital for both research and practical applications in various industries.