Company Filing History:
Years Active: 2006-2017
Title: The Innovative Contributions of Sun-Yran Chang in Cancer Treatment
Introduction: Sun-Yran Chang, based in Taipei, Taiwan, is a distinguished inventor known for his vital contributions to the field of pharmaceutical innovations. With a remarkable portfolio of 4 patents, he specializes in creating therapies aimed at combating cancer through novel chemical compositions and methodologies.
Latest Patents: Among his most notable patents is a pharmaceutical composition that combines sorafenib and GW5074. This groundbreaking combination therapy has been shown to inhibit cancer cell growth by leveraging the c-Raf-PP2A-DAPK signaling transduction pathway. The patent details a preclinical study on orthotopic spontaneous kidney cancer, highlighting that the bond formed between c-Raf and GW5074 leads to significant changes in conformation, thereby increasing the affinity for sorafenib. This binding process facilitates the dephosphorylation of DAPK at serine 308 by PP2A, inducing necrosis in cancer cells. Furthermore, serine 308 of the DAPK protein is proposed as a biomarker for drug screening, enhancing the potential for targeted cancer therapies.
Career Highlights: Sun-Yran Chang is currently affiliated with the National Defense Medical Center, a reputable institution where he conducts research and development on innovative treatments for cancer. His extensive work has not only advanced the understanding of cancer mechanisms but has also paved the way for developing therapeutic strategies that utilize specific biomarkers in drug screening.
Collaborations: Throughout his career, Sun-Yran Chang has collaborated with notable colleagues, including Guang-Huan Sun and Tai-Lung Cha, further enhancing his research output and broadening the impact of his groundbreaking discoveries in cancer treatment.
Conclusion: Sun-Yran Chang's innovative spirit and dedication to cancer research have led to significant advancements in pharmaceutical compositions and drug therapies. His contributions not only promise improved treatment options for cancer patients but also establish a solid foundation for future research in oncology, ensuring that his legacy as an inventor will have lasting effects in the medical field.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.