Sun-Hee Jung

Title: **Inventor Spotlight: Sun-Hee Jung**

Introduction

Sun-Hee Jung is an innovative inventor based in Bethesda, MD, who has made significant contributions to the field of biotechnology. With five patents to her name, she has focused her work on developing advanced methods in peptide technology and immunotherapy.

Latest Patents

One of Sun-Hee Jung's latest patents is titled "Methods of making recombinant disulfide-stabilized polypeptide fragments having binding specificity." This invention describes the creation of disulfide-stabilized recombinant polypeptide molecules that possess the ability to bind specifically to other peptides, such as the variable regions of antibody molecules. Additionally, the patent outlines methods for producing these molecules and includes nucleic acid sequences that encode them. Notably, it discloses Fv antibody fragments that are stabilized through a disulfide bond linking the V and V regions of the fragment, as well as similar stabilization methods for T cell receptor chains.

Another significant patent involves "Methods of inhibiting the growth of cells bearing LewisY antigens using B1, B3, or B5 targeted immunoconjugates." This invention provides methods to inhibit the growth of cells expressing Lewis antigens by utilizing a composition that includes specific Fv regions of monoclonal antibodies. The invention emphasizes the combination of the Fv regions with various effector molecules such as chemotherapeutic agents and toxins, which can be recombinantly fused for enhanced effectiveness.

Career Highlights

Throughout her career, Sun-Hee Jung has worked with prominent organizations, including the United States of America as represented by the Department of Health and the Government of the United States as represented by the Secretary of the Department of Health and Human Services. Her work has significantly contributed to advancements in medical treatments and drug development processes.

Collaborations

Sun-Hee Jung has collaborated with esteemed colleagues, including Ira H. Pastan and Byungkook Lee, which highlights her ability to work effectively within a team to push the boundaries of scientific innovation. These collaborations have undoubtedly influenced her research and the success of her patented inventions.

Conclusion

Sun-Hee Jung’s remarkable accomplishments and her ongoing contributions to the fields of biotechnology and immunotherapy solidify her standing as a prominent inventor. With multiple patents focusing on complex peptide technologies, she continues to shape the future of medical science, demonstrating the profound impact that dedicated inventors can have on society.