Location History:
- Croton-on-Hudson, NY (US) (2001 - 2010)
- Cortlandt Manor, NY (US) (2010 - 2016)
- Cortland Manor, NY (US) (2021)
Company Filing History:
5 out of 1,697 
2 out of 471 
2 out of 832,912 Years Active: 2001-2021
Title: Suman Laal: Innovator in Tuberculosis Detection
Introduction
Suman Laal is a notable inventor based in Cortlandt Manor, NY (US). He has made significant contributions to the field of medical diagnostics, particularly in the early detection of tuberculosis (TB) in immunocompromised individuals. With a total of 7 patents, Laal's work has the potential to improve health outcomes for those at high risk of developing active TB.
Latest Patents
One of Laal's latest patents focuses on peptides for a screening test for HIV positive patients at high risk for tuberculosis. This innovation provides peptides suitable for the early detection of active Mycobacterium tuberculosis (Mtb) infection in immunocompromised individuals. The peptides can form complexes with antibodies directed to Mtb antigens such as MS, MPT51, ESAT6, or CFPIO. The presence of these complexes aids in predicting the risk of developing active tuberculosis in these vulnerable populations. Additionally, Laal has identified several peptide epitopes and fragments from three Mtb cell wall proteins that serve as early antigens, inducing antibodies during Mtb infection in humans. These proteins include Proline-Threonine Repetitive Protein (PTRP), PE-PGRS51, and LipC. The peptides can be utilized as antigens for serological detection, allowing for earlier diagnosis of Mtb infection than conventional methods. Furthermore, these peptide-based compositions can be used as immunogens in TB vaccines, contributing to prevention and treatment strategies.
Career Highlights
Laal has worked with prestigious institutions, including New York University, where he has contributed to research and development in the field of infectious diseases. His innovative approaches have garnered attention and recognition within the scientific community.
Collaborations
Some of Laal's notable coworkers include Susan Zolla-Pazner and John T Belisle. Their collaborative efforts have further advanced the understanding and detection of tuberculosis.
Conclusion
Suman Laal's contributions to the field of tuberculosis detection through his innovative patents highlight the importance of early diagnosis and intervention in public health. His work continues to pave the way for advancements in medical diagnostics and treatment options.