Company Filing History:
Years Active: 2021-2024
Title: Innovations in Cancer Research by Sujeewa Ranatunga Mahanthe Mudiyanselage
Introduction
Sujeewa Ranatunga Mahanthe Mudiyanselage is a prominent inventor based in Tampa, FL, who has made significant contributions to cancer research. He holds four patents that focus on innovative approaches to combat non-small cell lung cancer. His work is particularly notable for its potential to improve treatment outcomes for patients.
Latest Patents
Among his latest patents are YAP1 inhibitors that target the interaction of YAP1 with OCT4. The binding of the transcriptional co-activator YAP1 to the transcription factor Oct4 induces Sox2, a transcription factor necessary for the self-renewal of stem-like cells from non-small cell lung cancer. The WW domain of YAP1 binds to the PPxY motif of Oct4 to induce Sox2. Delivering a peptide corresponding to the WW domain could prevent the induction of Sox2 and stemness. Similarly, peptides and mimetics of the PPxY motif would be able to inhibit stemness. His patents disclose compounds that affect the Yap1:Oct4 interaction, showcasing his innovative approach to cancer treatment.
Career Highlights
Sujeewa is affiliated with the H. Lee Moffitt Cancer Center and Research Institute, Inc., where he conducts his research. His work has garnered attention for its potential to revolutionize cancer therapies and improve patient outcomes.
Collaborations
He collaborates with esteemed colleagues such as Srikumar Chellappan and Nicholas James Lawrence, contributing to a dynamic research environment focused on cancer innovation.
Conclusion
Sujeewa Ranatunga Mahanthe Mudiyanselage's contributions to cancer research through his patents and collaborations highlight the importance of innovation in the fight against cancer. His work continues to pave the way for new therapeutic strategies.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.