Sui-Lam Wong

Title: Sui-Lam Wong: Innovator in Streptavidin Muteins

Introduction

Sui-Lam Wong is a notable inventor based in Calgary, Canada. He has made significant contributions to the field of biochemistry, particularly in the development of streptavidin muteins. With a total of four patents to his name, Wong's work has the potential to impact various applications in biotechnology.

Latest Patents

Wong's latest patents include innovative streptavidin muteins that exhibit reversible binding for biotin and streptavidin binding peptide tagged proteins. The first patent describes a mutein that binds both streptavidin binding peptide tagged and biotin or biotinylated molecules in a reversible manner. This characteristic allows for stability and reuse, making it a cost-effective solution in production. The second patent focuses on a tetrameric streptavidin mutein with reversible biotin binding capability. This mutein can oligomerize to form tetramers, demonstrating strong subunit interactions and a favorable dissociation constant for biotin. The mutein is also designed to be produced with reasonable yield without the need for complex refolding processes.

Career Highlights

Wong is currently associated with Uti Limited Partnership, where he continues to advance his research and development efforts. His work is characterized by a commitment to innovation and practical applications in the field of biochemistry.

Collaborations

Wong collaborates with talented individuals such as Sau-Ching Wu and Isabelle Barrette-Ng, who contribute to his research endeavors. Their combined expertise enhances the potential for groundbreaking discoveries in their field.

Conclusion

Sui-Lam Wong's contributions to the development of streptavidin muteins highlight his innovative spirit and dedication to advancing biochemistry. His patents reflect a commitment to creating practical solutions that can be utilized in various applications.