Company Filing History:
Years Active: 1997-1998
Title: Sueharu Horinouch: Innovator in Nitrile Hydratase Technology
Introduction
Sueharu Horinouch is a prominent inventor based in Tokyo, Japan. He has made significant contributions to the field of biotechnology, particularly in the development of nitrile hydratase technology. With a total of 4 patents to his name, Horinouch has established himself as a key figure in this innovative area.
Latest Patents
Horinouch's latest patents include groundbreaking inventions related to gene encoding a polypeptide having nitrile hydratase activity. One of his notable inventions involves a gene derived from the Pseudomonas chlororaphis B23 strain, which encodes a polypeptide capable of hydrating nitriles to amides. This invention also encompasses a recombinant DNA containing the gene and a transformant that has been transformed with the recombinant DNA. Furthermore, he has developed a method for producing nitrile hydratase using the transformant and for synthesizing amides using nitrile hydratase. Another significant patent discloses the amino acid and nucleotide sequences of the alpha and beta subunits of two types of nitrile hydratase derived from Rhodococcus rhodochrous J-1. This DNA fragment encoding nitrile hydratase is inserted into an expression vector, allowing for the transformation of microorganisms to produce higher levels of nitrile hydratase compared to conventional methods.
Career Highlights
Throughout his career, Horinouch has worked with various companies, including Nitto Chemical Industry Co., Ltd. His work has significantly advanced the understanding and application of nitrile hydratase in biotechnology.
Collaborations
Horinouch has collaborated with notable individuals in his field, including Toru Nagasawa and Teruhiko Beppu. These collaborations have further enhanced his research and development efforts.
Conclusion
Sueharu Horinouch is a distinguished inventor whose work in nitrile hydratase technology has made a lasting impact on biotechnology. His innovative patents and collaborations continue to drive advancements in this important field.