Company Filing History:
1 out of 832,880 Years Active: 2002
Title: Subrahmanyam V Yerramilli: Innovator in Gene Expression Research
Introduction
Subrahmanyam V Yerramilli is a notable inventor based in Montgomery Village, MD (US). He has made significant contributions to the field of gene expression research, particularly in understanding granulocytic cells. His innovative work has implications for therapeutic developments in inflammatory diseases.
Latest Patents
Yerramilli holds a patent for a process to study changes in gene expression in granulocytic cells. This invention comprises a method to identify granulocytic cell genes that are differentially expressed upon exposure to a pathogen or in a sterile inflammatory disease. The method involves preparing a gene expression profile of a granulocytic cell population exposed to a pathogen or isolated from a subject with a sterile inflammatory disease. This profile is then compared to that of quiescent granulocytic cells. The invention is particularly useful for identifying cytokine genes, genes encoding cell surface receptors, and genes encoding intermediary signaling molecules. Additionally, it includes methods to identify therapeutic agents that modulate the expression of at least one gene in a granulocytic population.
Career Highlights
Throughout his career, Yerramilli has focused on advancing the understanding of gene expression in relation to immune responses. His work has contributed to the identification of genes that are differentially expressed during neutrophil contact with pathogens, which is crucial for developing targeted therapies.
Collaborations
Yerramilli has collaborated with esteemed colleagues such as Yatindra Prashar and Peter E Newburger. These collaborations have further enriched his research and contributed to the advancement of knowledge in the field.
Conclusion
Subrahmanyam V Yerramilli's innovative work in gene expression research highlights the importance of understanding granulocytic cells in the context of disease. His contributions pave the way for future therapeutic developments in treating inflammatory conditions.