Company Filing History:
Years Active: 1986-1988
Title: Innovations by Stuart G Fischer
Introduction
Stuart G Fischer is a notable inventor based in New York, NY, who has made significant contributions to the field of DNA purification and concentration. With a total of two patents to his name, Fischer's work has advanced the methodologies used in genetic research and diagnostics.
Latest Patents
Fischer's latest patents focus on a process and apparatus for purifying and concentrating DNA from crude mixtures, particularly from human whole blood samples. The patented technology allows for the collection of DNA that is of usable volume and concentration, ensuring a level of purity that permits conventional restriction by various enzymes without the need for further purification. The apparatus consists of an agarose gel disc, typically 5 mm thick and 31 mm in diameter, which is immersed in an electrophoresis buffer solution. This gel disc is supported between two 8 micrometer polycarbonate filters within an electric field. The method involves loading a treated sample, such as blood lysate, onto the agarose gel disc and applying an electric field. The DNA molecules, being the largest in terms of molecular weight, are impeded in their passage through the gel, while other components of the treated blood are swiftly removed by the buffer solution. The DNA is then eluted and collected in a concentrated form, thanks to the application of the electric field.
Career Highlights
Stuart G Fischer has established himself as a key figure in the biotechnology sector through his innovative work at Lifecodes Corporation. His expertise in DNA purification techniques has positioned him as a valuable asset in the field of genetic research.
Collaborations
Fischer has collaborated with notable colleagues such as Graham J Tomblin and Karen B Wexler, contributing to advancements in their shared field of expertise.
Conclusion
Stuart G Fischer's contributions to DNA purification and concentration represent significant advancements in biotechnology. His innovative patents and collaborative efforts continue to influence the field positively.
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