Company Filing History:
Years Active: 2001
Title: The Innovations of Stuart Emanuel
Introduction
Stuart Emanuel is a notable inventor based in New Brunswick, NJ (US). He has made significant contributions to the field of biotechnology, particularly in the area of interferon gamma and its receptor. His work has implications for understanding and manipulating human genomic DNA.
Latest Patents
Stuart Emanuel holds 1 patent for his invention titled "Accessory factory function for interferon gamma and its receptor." This invention encompasses several key components: (a) a 540 kb YAC that encodes necessary species-specific factors, substituting for human Chromosome 21 to reconstitute the Hu-IFN-gamma receptor-mediated induction of class I HLA antigens; (b) the construction of a plasmid to integrate a selective marker for antibiotic G418 resistance into YACs, facilitating the manipulation of human genomic DNA; (c) two fragmentation vectors, pSE1 and pSE2, developed for targeting YACs containing human genomic DNA; (d) a chromosomal fragmentation procedure to produce a deletion set of YACs from a parental YAC known to map to Chromosome 21q; and (e) the isolation of cDNA clones that encode the necessary species-specific factor.
Career Highlights
Stuart Emanuel has been associated with the University of Medicine and Dentistry of New Jersey, where he has contributed to various research initiatives. His work has advanced the understanding of genetic factors related to interferon gamma, which is crucial for immune response.
Collaborations
Throughout his career, Stuart has collaborated with notable scientists such as Sidney Pestka and Serguei V Kotenko. These collaborations have enriched his research and expanded the impact of his inventions.
Conclusion
Stuart Emanuel's innovative work in biotechnology, particularly regarding interferon gamma, showcases his significant contributions to the field. His patent reflects a deep understanding of genetic manipulation and its potential applications in medicine.