Company Filing History:
Years Active: 1987-1994
Title: **Innovations of Steven W. Herring: Pioneering Advances in Factor Purification**
Introduction
Steven W. Herring, an accomplished inventor based in San Dimas, California, has made significant contributions to the field of biochemistry with a focus on the purification of crucial blood factors. With a total of four patents to his name, Herring's inventions reflect his dedication to improving healthcare through innovative methodologies.
Latest Patents
Among his latest patents, Herring has developed the following noteworthy processes:
1. **Purification of Factor IX** - This invention pertains to a novel process for purifying Factor IX from impure protein fractions. It incorporates the addition of a solvent and detergent to the protein fraction to effectively inactivate viral contaminants. His innovative purification methodology utilizes chromatography on a sulfated polysaccharide resin without prior removal of the solvent and detergent, resulting in Factor IX with a specific activity of at least 85 units/mg.
2. **Plasma Fraction Purification** - Herring's second recent patent outlines a method for activating Factor II to Factor II.a. This process involves incubating Factor II in conjunction with Factors V, X.a, phospholipids, and calcium ions, all derived from a single impure protein fraction. The purification steps include DEAE ligand chromatography followed by a barium chloride precipitation, leading to the effective recovery of the necessary factors.
Career Highlights
As an inventor at Alpha Therapeutic Corporation, Steven Herring has continuously worked towards advancing biopharmaceutical applications. His detailed understanding of biochemical processes and innovative thinking has led to significant breakthroughs in blood factor purification techniques, enhancing safety and efficacy in therapeutic applications.
Collaborations
Throughout his career, Herring has collaborated with esteemed colleagues such as Yahiro Uemura and Munehiro Noda. Their joint efforts contribute to the development of cutting-edge technologies within the pharmaceutical industry, showcasing the power of teamwork in scientific advancements.
Conclusion
Steven W. Herring stands out as a prominent inventor dedicated to enhancing healthcare through innovative purification processes. His latest patents not only reflect his expertise but also exemplify the potential for future breakthroughs in the biopharmaceutical domain. Through his work at Alpha Therapeutic Corporation and collaborations with fellow innovators, Herring continues to make a lasting impact on the field of biochemistry.