Steven S Scherer

Title: Steven S Scherer: Innovator in Neuropathy Research

Introduction

Steven S Scherer is a notable inventor based in Media, PA (US). He has made significant contributions to the field of neuropathy research, particularly in relation to Charcot-Marie-Tooth disease 2A (CMT2A). His work focuses on developing rat models that help in understanding the pathogenesis and treatment of this debilitating condition.

Latest Patents

Scherer holds a patent for "Rat models for CMT2A that develop a progressive neuropathy." This invention relates to CMT2A harboring the p.Arg364Trp or p.His361Tyr Mfn2 mutation. The human counterpart of this mutation results in severe, early-onset axonal neuropathy. The research involved characterizing cohorts of mutants and wild-type littermates, revealing multiple motor deficits that worsened over time. The study also highlighted reduced density of myelinated axons and active axonal degeneration in distal nerves, as well as significant findings in the cervical spinal cord.

Career Highlights

Throughout his career, Scherer has worked with prominent organizations such as the Charcot-Marie-Tooth Association and the University of Pennsylvania. His research has been pivotal in advancing the understanding of CMT2A and its implications for treatment.

Collaborations

Scherer has collaborated with notable colleagues, including Mark Albert Scheideler and Guojun Zhao. Their combined efforts have contributed to the depth of research in neuropathy and related fields.

Conclusion

Steven S Scherer is a distinguished inventor whose work in neuropathy research has the potential to impact the lives of many affected by CMT2A. His innovative approaches and collaborations continue to drive advancements in this critical area of medical research.