Company Filing History:
4 out of 1,618 
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3 out of 832,812 Years Active: 2003-2021
Title: The Innovative Contributions of Steven Ripp
Introduction
Steven Ripp is a notable inventor based in Knoxville, TN, with a remarkable portfolio of eight patents. His work primarily focuses on advancements in bioluminescence and cellular engineering, showcasing his commitment to innovation in the field of biotechnology.
Latest Patents
Among his latest patents is a groundbreaking invention titled "Lux expression in cells and methods of use." This patent describes cells, including stem cells, that possess an autobioluminescent phenotype. These cells emit a luminescent signal without the need for an external luminescent stimulator. The luminescent signal can be constitutive, inducible, repressible, or tissue-specific. The cells are engineered to express a synthetic bacterial luciferase (lux) cassette, specifically the luxCDABEfrp gene cassette. Notably, the expression levels of luxC, luxD, luxE, and flavin reductase in these cells can be ten to forty times greater than that of luxA and luxB. Additionally, methods for creating and utilizing these cells are disclosed.
Another significant patent is the "Microluminometer chip and method to measure bioluminescence." This invention features an integrated microluminometer that includes a circuit chip with a photodetector designed to convert light into a photocurrent. The design incorporates a distributed electrode configuration to enhance efficiency, making it a valuable tool for measuring bioluminescence.
Career Highlights
Steven Ripp has made significant contributions to the field of biotechnology through his work at various organizations, including UT-Battelle, Inc. His innovative research has led to advancements that have the potential to impact various applications in science and medicine.
Collaborations
Throughout his career, Steven has collaborated with esteemed colleagues such as Gary S. Sayler and Bruce Michael Applegate. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and innovation.
Conclusion
Steven Ripp's contributions to the field of biotechnology through his patents and collaborations highlight his role as a leading inventor. His work continues to pave the way for future innovations in cellular engineering and bioluminescence.