This inventor holds 6 USPTO granted patents. Top assignees: Arizona Biomedical Research Commission, The Arizona Disease Control Research Commission. Active years: 2003-2011.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Tempe, AR (US) (2006)
- Tempe, AZ (US) (2003 - 2011)
Company Filing History:
3 out of 11 
3 out of 5 Years Active: 2003-2011
Title: Innovations and Contributions of Steven R. Ottersberg
Introduction
Steven R. Ottersberg is a notable inventor based in Tempe, Arizona, with a significant contribution to the field of cancer research. He holds a total of six patents, showcasing his dedication to developing innovative solutions for complex medical challenges. His work primarily focuses on anticancer agents that target protein prenylation, a crucial process in cancer cell growth.
Latest Patents
One of Steven R. Ottersberg's latest patents involves anticancer agents based on the regulation of protein prenylation. Oncoproteins such as Ras and RhoB are known to induce unrestrained cell division when localized at the inner surface of a cancer cell membrane. This localization is facilitated by the prenylation reaction, where a hydrophobic group, such as a farnesyl group, is attached to the protein in the presence of an enzyme like farnesyl protein transferase. By deactivating the prenylation enzyme through covalent modification, it is possible to mitigate or cease cancer cell growth. His research includes various prenylation inhibitors that bond covalently to the prenylation enzyme, including carbonyl or thiocarbonyl compounds and alpha oxo-epoxides, which are bonded to a hydrophobic, substrate-mimicking group.
Career Highlights
Throughout his career, Steven has worked with esteemed organizations such as the Arizona Disease Control Research Commission and the Arizona Biomedical Research Commission. His experience in these institutions has allowed him to contribute significantly to the advancement of medical research and innovation.
Collaborations
Steven R. Ottersberg has collaborated with notable colleagues, including Seth David Rose and Karl J. Okolotowicz. These partnerships have further enriched his research and development efforts in the field of cancer treatment.
Conclusion
Steven R. Ottersberg's innovative work in developing anticancer agents highlights his commitment to improving healthcare outcomes. His contributions to the understanding of protein prenylation and its implications in cancer cell growth are invaluable. His ongoing research continues to pave the way for potential breakthroughs in cancer treatment.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile