Steven R Duff

Title: The Innovative Contributions of Steven R. Duff

Introduction

Steven R. Duff is a notable inventor based in De Soto, Kansas, who has made significant contributions to the field of chemistry. With a total of 2 patents, his work focuses on the synthesis of chiral amines and imines, which are crucial in various pharmaceutical applications.

Latest Patents

Duff's latest patents include a method for the preparation of (R)-N-[1-(3-methoxyphenyl)ethyl]-3-(2-chlorobenzene)propanamine. This innovative process involves reducing the appropriate amidyl or iminyl precursor using a suitable reducing agent. The precursor is synthesized from (R)-3-methoxy-.alpha.-methylbenzylamine. Additionally, he has developed a method for condensing a nitrile with a primary or secondary amine to form an imine. This reaction utilizes diisobutylaluminum hydride and is particularly effective for producing enantiomerically pure chiral imines, which can ultimately lead to the formation of amines.

Career Highlights

Steven R. Duff is currently associated with NPS Pharmaceuticals, Inc., where he continues to advance his research and development efforts. His work has been instrumental in enhancing the understanding and application of chiral compounds in the pharmaceutical industry.

Collaborations

Some of his notable coworkers include Bradford C. VanWagenen and William A. Nelson, who have collaborated with him on various projects, contributing to the success of their research endeavors.

Conclusion

Steven R. Duff's innovative work in the field of chemistry, particularly in the synthesis of chiral compounds, showcases his significant contributions to the industry. His patents reflect a commitment to advancing pharmaceutical science and improving the efficacy of drug development.