Steven C Hand

Title: Innovations in Protein Preservation: The Patents of Steven C. Hand

Introduction

Steven C. Hand, an accomplished inventor based in Louisville, Colorado, has made significant contributions to the field of protein preservation. With two patents under his name, he has focused on methods that enhance the stability and biological activity of proteins during freezing. His inventive techniques have important implications in pharmaceuticals, where the integrity of proteins is crucial for therapeutic applications.

Latest Patents

Hand's latest innovations include the following patents:

1. **Cryogenic protection of phosphofructokinase using amino acids and zinc** - This method involves protecting soluble proteins from denaturation after freezing by treating them with an amino acid or trimethylamine-N-oxide and a transition metal ion before freezing. The approach allows for the preservation of the biological activity of delicate proteins, allowing them to be thawed and administered directly without the need to remove the cryoprotectant.

2. **Cryogenic protectant for proteins** - This patent outlines a method for preserving the biological activity of proteins by exposing them to a carbohydrate and a transition metal ion prior to freezing. The treated proteins can be thawed or rehydrated without loss of functionality, further enhancing applications in the pharmaceutical sector.

Career Highlights

Steven C. Hand works at the University of Southwestern Louisiana, where he engages in groundbreaking research on protein stability and preservation. His focus on cryoprotection techniques showcases his dedication to improving the storage and distribution of vital pharmaceutical proteins, thus making a significant impact in the biomedical field.

Collaborations

Throughout his career, Hand has collaborated with esteemed colleagues, including John F. Carpenter and John H. Crowe. These collaborations likely facilitate the advancement of research, allowing for cross-disciplinary insights into protein preservation and its applications.

Conclusion

Steven C. Hand is a notable inventor whose work on protein cryoprotection holds promise for revolutionizing the preservation of biologically active proteins. His patents not only enhance the stability of delicate proteins but also ensure their efficacy in therapeutic settings. As the demand for innovative solutions in pharmaceuticals continues to grow, Hand's contributions will undoubtedly play a vital role in shaping future advancements.