Steven A Kates

Title: Steven A. Kates: Innovator in Automated Peptide Synthesis

Introduction

Steven A. Kates is a notable inventor based in Newton, MA (US). He has made significant contributions to the field of peptide synthesis, particularly through his innovative methods that enhance the efficiency of chemical processes. With a total of 2 patents to his name, Kates continues to push the boundaries of scientific research and application.

Latest Patents

One of Kates' latest patents is focused on "Automated allyl deprotection in solid-phase synthesis." This method involves the removal of an allyl protecting group from an allyl-protected derivative of a biologically relevant amino acid. A key aspect of this method is the use of a soluble organometallic catalyst, specifically an organopalladium catalyst. The preferred catalyst is soluble tetrakistriphenylphosphine palladium (0). This allyl deprotection method is designed for use on instruments for automated peptide synthesis. Additionally, the patent discloses methods for preparing the soluble organometallic catalyst and outlines various soluble catalyst compositions.

Career Highlights

Kates is currently associated with Perseptive Biosystems Inc., where he applies his expertise in peptide synthesis and catalysis. His work has been instrumental in advancing automated processes in the field, making significant strides in the efficiency and effectiveness of peptide synthesis.

Collaborations

Kates has collaborated with notable professionals in his field, including Fernando Albericio. These collaborations have further enriched his research and development efforts, leading to innovative solutions in peptide synthesis.

Conclusion

Steven A. Kates is a prominent figure in the realm of automated peptide synthesis, with a focus on innovative methods that utilize organometallic catalysts. His contributions continue to influence the field, showcasing the importance of innovation in scientific research and application.