Steven A Feldman

Title: Innovations and Contributions of Steven A. Feldman

Introduction

Steven A. Feldman is a notable inventor based in Redwood City, California. He has made significant contributions to the field of immunology, particularly in the development of T cell receptors for cancer treatment. With a total of five patents to his name, Feldman's work has the potential to impact cancer therapies significantly.

Latest Patents

Feldman's latest patents include innovative methods and compositions related to T cell receptors. One of his notable inventions is a T cell receptor (TCR) that recognizes melanoma antigen family A (MAGE A)-3 in the context of HLA-A1 and MAGE-A12 in the context of HLA-Cw7. This invention provides isolated or purified TCRs, related polypeptides, proteins, nucleic acids, recombinant expression vectors, host cells, and populations of cells. Additionally, it includes antibodies and pharmaceutical compositions related to these TCRs, along with methods for detecting cancer and treating or preventing it in hosts. Another significant patent involves methods for selectively expanding T cells expressing a TCR with a murine constant region. This method includes modifying human T cells to express a TCR, producing a population of cells, and culturing them in specific conditions to enhance the number of T cells expressing the TCR.

Career Highlights

Feldman has worked with prestigious organizations, including the National Institutes of Health, a component of the US Department of Health & Human Services, and Kite Pharma, Inc. His experience in these institutions has allowed him to contribute to groundbreaking research in cancer immunotherapy.

Collaborations

Throughout his career, Feldman has collaborated with esteemed colleagues such as Steven A. Rosenberg and Paul F. Robbins. These collaborations have further enriched his research and innovations in the field.

Conclusion

Steven A. Feldman's contributions to immunology and cancer treatment through his patents and collaborations highlight his role as a significant inventor in the field. His work continues to pave the way for advancements in cancer therapies.