This inventor holds 3 USPTO granted patents. Top assignees: Bayer Corporation, Bayer Healthcare LLC. Active years: 2002-2009.
Company Filing History:
Years Active: 2002-2009
Title: Steve R Petteway: Innovator in Transmissible Spongiform Encephalopathy Detection
Introduction
Steve R Petteway is a notable inventor based in Cary, NC (US). He has made significant contributions to the field of immunoassays, particularly in the detection of transmissible spongiform encephalopathy (TSE) proteins. With a total of 3 patents, his work has advanced the understanding and detection of prion-related diseases.
Latest Patents
One of his latest patents is focused on the "Detection of transmissible spongiform encephalopathy (TSE) protein employing a highly sensitive Western blot assay and chemiluminescent detection system." This invention provides a rapid and sensitive immunoassay capable of detecting and quantifying pathogenic proteins to a level of 3 to 5 logs. The preferred immunoassay utilized is a chemiluminescent endpoint for a Western blot immunoassay. This invention has been successfully applied to track the clearance of pathogenic proteins during the production of proteins derived from plasma. It is particularly applicable and has been confirmed by bioassay to relate TSE infectivity to quantitative results on prion protein.
Another significant patent is the "Rapid method of determining clearance of prion protein." Transmissible spongiform encephalopathies (TSEs) are a class of fatal, neurodegenerative diseases found in many mammalian species. This invention is directed toward a rapid, specific, sensitive, and quantitative method for the detection of TSE clearance from a plasma product utilizing a chemiluminescent Western blot immunoassay. This immunoassay format can detect picogram concentrations of PrP (proteinase resistant PrP fragment) and is linear over a 3-5 log range. The invention is useful for tracking the clearance of PrP during plasma manufacturing processes.
Career Highlights
Steve R Petteway has worked with prominent companies such as Bayer Corporation and Bayer Healthcare LLC. His experience in these organizations has contributed to his expertise in the field of immunoassays and prion detection.
Collaborations
Some of his notable coworkers include Douglas C Lee and Robert W Kozak. Their collaboration has likely played a role in advancing the research and development of TSE detection methods.
Conclusion
Steve R Petteway