Company Filing History:
Years Active: 2014-2018
Title: Steve J DeMarco: Innovator in Peptidomimetics
Introduction
Steve J DeMarco is a notable inventor based in Dietgen, Switzerland. He has made significant contributions to the field of medicinal chemistry, particularly in the development of peptidomimetics. With a total of two patents to his name, his work focuses on innovative solutions for treating various diseases.
Latest Patents
DeMarco's latest patents include the development of template-fixed β-hairpin peptidomimetics. These compounds are characterized by a general formula where Z represents a template-fixed chain of four α-amino acid residues. Depending on their positions in the chain, these residues can be Gly or other specified types. The peptidomimetics have the ability to agonize or antagonize GPCR receptors such as CXCR3, urotensin, and CCR10. They are designed to be used as medicaments for treating or preventing a range of diseases, including cardiovascular disorders, dermatological disorders, endocrine system and hormone disorders, metabolic diseases, inflammatory diseases, neurological diseases, respiratory diseases, haematological diseases, and cancer. The manufacturing process for these β-hairpin peptidomimetics is based on a mixed solid- and solution-phase synthetic strategy.
Career Highlights
Steve J DeMarco is currently associated with Polyphor Ltd., where he continues to advance his research in the field of peptidomimetics. His innovative work has positioned him as a key figure in the development of new therapeutic agents.
Collaborations
Some of his notable coworkers include Daniel Obrecht and Frank Gombert, who contribute to the collaborative efforts in research and development at Polyphor Ltd.
Conclusion
Steve J DeMarco's contributions to the field of medicinal chemistry through his innovative patents highlight his role as a significant inventor. His work in developing peptidomimetics has the potential to impact the treatment of various diseases significantly.