Location History:
- Buckinghamshire, GB (1987 - 1990)
- Milton Keynes, GB (1989 - 1991)
Company Filing History:
Years Active: 1987-1991
Title: Innovations of Stephen R. Fletcher
Introduction
Stephen R. Fletcher is a notable inventor based in Buckinghamshire, GB. He has made significant contributions to the field of pharmaceuticals, particularly in the development of antineoplastic agents. With a total of 4 patents, his work has had a considerable impact on cancer treatment.
Latest Patents
Fletcher's latest patents include innovative compounds such as Pyrido[2,3-]pyrimidine derivatives. These compounds, specifically the 2,4-Diamino- and 2-amino-4-hydroxy- derivatives of N-(4-[2-(pyrido[2,3-d]pyrimidin-6-yl)alkyl]benzoyl)-L-glutamic acids, are recognized for their antineoplastic properties. The preparation of these compounds involves hydrolytic or hydrogenolytic removal of carboxylic acid protecting groups from the corresponding protected glutamic acid derivatives. A typical embodiment of this innovation is N-(4-[2-(2-amino-4-hydroxy-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-6-yl)ethyl]benzoyl)-L-glutamic acid. Additionally, he has developed diastereoisomeric tetrahydropyrido-(2,3,d) pyrimidine derivatives, which also serve as antineoplastic agents. These compounds are prepared by separating the diastereoisomeric forms of the correspondingly protected glutamic derivatives and removing carboxylic acid and/or amino protecting groups.
Career Highlights
Stephen R. Fletcher is affiliated with Princeton University, where he continues to advance his research in medicinal chemistry. His work has been instrumental in the development of new therapeutic agents aimed at combating cancer.
Collaborations
Fletcher has collaborated with esteemed colleagues such as Edward C. Taylor and George P. Beardsley, contributing to the advancement of innovative pharmaceutical solutions.
Conclusion
Stephen R. Fletcher's contributions to the field of pharmaceuticals, particularly through his innovative patents, highlight his role as a significant inventor in the development of antineoplastic agents. His work continues to influence cancer treatment and research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.