Company Filing History:
Years Active: 1997
Title: The Innovations of Stephen M Searle
Introduction
Stephen M Searle is a notable inventor based in Bath, GB. He has made significant contributions to the field of biotechnology, particularly in the development of humanized rodent antibodies. His work focuses on enhancing therapeutic efficacy through innovative methods.
Latest Patents
One of Stephen M Searle's key patents is related to the resurfacing of rodent antibodies. This invention outlines a method for providing humanized rodent antibodies that exhibit improved therapeutic efficacy due to the presentation of a human surface in the variable region. The patent details a systematic approach involving the alignment of antibody heavy and light chain variable regions, identification of amino acid residues, and the production of humanized antibodies with specific binding capabilities.
Career Highlights
Stephen M Searle is currently associated with Immunogen, Inc., where he continues to advance his research and development efforts. His work has been instrumental in the field of antibody engineering, contributing to the creation of more effective therapeutic agents.
Collaborations
Throughout his career, Stephen has collaborated with esteemed colleagues such as Jan T Pedersen and Anthony R Rees. These partnerships have fostered a collaborative environment that enhances innovation and research outcomes.
Conclusion
Stephen M Searle's contributions to the field of biotechnology, particularly through his patent on humanized rodent antibodies, highlight his role as an influential inventor. His work continues to pave the way for advancements in therapeutic applications.