Company Filing History:
Years Active: 1998-2001
Title: The Innovative Contributions of Stephen J Russell
Introduction
Stephen J Russell is a notable inventor based in Cambridge, GB. He has made significant contributions to the field of biotechnology, particularly in the development of recombinant viruses and their applications in gene delivery. With a total of 3 patents to his name, Russell's work has the potential to impact various medical and research fields.
Latest Patents
One of Russell's latest patents involves recombinant viruses displaying a nonviral polypeptide on their external surface. This innovation focuses on creating retrovirus particles that display functional antibody fragments. By fusing the gene encoding an antibody fragment directed against a hapten with the gene encoding the viral envelope protein of the ecotropic Moloney murine leukemia virus, Russell has enabled the recovery of retroviral particles with specific hapten-binding activities. These particles can transfer genes to mouse fibroblasts, showcasing their potential for targeted gene delivery and the construction of viral display libraries.
Another significant patent pertains to binding assays. This method tests substances for their ability to affect the formation or oligomerization of a complex comprising members of a specific binding pair. The method involves reacting lipid-enveloped particles with cells in the presence of the substance under test, allowing for the detection of transferred labels. This innovative approach could enhance the understanding of cellular interactions and the development of new therapeutic strategies.
Career Highlights
Throughout his career, Stephen J Russell has worked with esteemed organizations such as the Medical Research Council and Cambridge Drug Discovery Holdings Ltd. His experience in these institutions has allowed him to contribute to groundbreaking research and development in the field of biotechnology.
Collaborations
Russell has collaborated with notable individuals in his field, including Robert E Hawkins and Gregory Paul Winter. These collaborations have likely enriched his research and expanded the impact of his innovations.
Conclusion
Stephen J Russell's contributions to biotechnology through his patents and collaborations highlight his role as an influential inventor. His work in recombinant viruses and binding assays demonstrates the potential for advancements in gene delivery and therapeutic applications.