Location History:
- Cherry Hills Village, CO (US) (1996)
- Denver, US (1996)
- Denver, CO (US) (1995 - 2004)
Company Filing History:
9 out of 24 
2 out of 13 
1 out of 259 
Years Active: 1995-2004
Title: Discovering Innovations by Stephen J. Hoffman
Introduction
Stephen J. Hoffman, based in Denver, CO, is a notable inventor with an impressive track record of 11 patents to his name. His contributions primarily focus on the field of hemoglobin and its applications, showcasing significant advancements in biotechnology and synthetic biology.
Latest Patents
Hoffman's latest patents include groundbreaking inventions such as "DNA encoding fused di-alpha globins and use thereof." This innovation presents a novel molecule known as di-alpha globin, a single polypeptide chain created by connecting two alpha subunits, either directly or through a flexible linker. This approach allows di-alpha globin to be combined with beta globin and heme, forming hemoglobin through recombinant DNA techniques. Another significant patent pertains to "hemoglobins with intersubunit disulfide bonds." This invention utilizes recombinant DNA techniques to produce cysteine substitution mutants of alpha and beta globin, resulting in mutant hemoglobins that are crosslinked by disulfide bonds. These solutions serve as potential blood substitutes, especially when designed to reduce their affinity for oxygen.
Career Highlights
Throughout his career, Stephen J. Hoffman has made substantial contributions to various biotechnology companies. He has worked with Somatogen, Inc. and Baxter Biotech Technology Sarl, where he applied his expertise in recombinant DNA technologies to push the boundaries of hemoglobin research.
Collaborations
Hoffman's work has often involved collaborations with esteemed colleagues such as Kiyoshi Nagai and Douglas L. Looker. These partnerships have been instrumental in advancing their shared goals in the field of biotechnology.
Conclusion
Stephen J. Hoffman's innovative work in the realm of hemoglobin and synthetic biology continues to pave the way for new medical applications and blood substitutes. His patents and collaborations demonstrate a commitment to scientific progress and the potential impact of his inventions on healthcare.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.