Company Filing History:
Years Active: 1989-2000
Title: The Innovative Contributions of Stephen A. Sherwin
Introduction
Stephen A. Sherwin is a notable inventor based in San Francisco, CA. He has made significant contributions to the field of genetic engineering and cellular therapies. With a total of 5 patents, his work has advanced the understanding and application of gene manipulation techniques.
Latest Patents
One of Sherwin's latest patents focuses on gene manipulation and expression using genomic elements. This invention allows for the expression of mammalian target genes by employing chromosomal target DNA, either from native primary cells or yeast artificial chromosomes (YACs) in a yeast host. The YACs include a fragment of a mammalian chromosome that comprises the target gene. By utilizing homologous recombination, an amplifiable gene can be integrated into the mammalian fragment, enabling amplification. The resulting construct can then be transformed into a mammalian expression host, allowing for high yields of desired proteins.
Another significant patent by Sherwin involves combined cellular and immunosuppressive therapies. This innovation provides novel regimens for administering genetically modified allogeneic cells to a host. By combining the administration of these cells with a reduced regimen of an immunosuppressive agent, the therapy aims to treat various diseased states effectively.
Career Highlights
Throughout his career, Stephen A. Sherwin has worked with prominent companies in the biotechnology sector, including Cell Genesys, Inc. and Genentech, Inc. His experience in these organizations has contributed to his expertise in genetic research and development.
Collaborations
Sherwin has collaborated with notable professionals in his field, including Sue Klapholz and Arthur I. Skoultchi. These collaborations have further enriched his work and expanded the impact of his inventions.
Conclusion
Stephen A. Sherwin's innovative contributions to genetic engineering and cellular therapies have made a lasting impact on the field. His patents reflect a commitment to advancing scientific knowledge and improving therapeutic approaches.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.