Company Filing History:
Years Active: 2003-2006
Title: The Innovative Contributions of Stephen A. Baum
Introduction
Stephen A. Baum is a notable inventor based in Tucson, AZ. He has made significant contributions to the field of chemical synthesis, particularly in the development of combinatorial libraries. With a total of 3 patents, his work has advanced the methodologies used in molecular synthesis.
Latest Patents
One of his latest patents is titled "Apparatus and method for synthesizing combinatorial libraries." This invention describes an apparatus and method for synthesizing a combinatorial library comprising a plurality of chemical compounds. The unique aspect of this invention is that the chemical composition of each compound can be easily tracked. The library compounds are synthesized on solid-phase supports, which are spatially arranged in frames during synthesis according to a predetermined protocol. This allows each solid-phase support to pass through a series of unique spatial 2D or 3D addresses, enabling the determination of the chemical composition of each compound at any point during synthesis. The solid-phase supports include hollow tubular-shaped lanterns and gears.
Another significant patent is "Three-dimensional array of supports for solid-phase parallel synthesis and method of use." This patent presents a three-dimensional (3D) array of solid-phase supports designed for parallel synthesis of a library of molecules with 3D diversity. Individual locations in the 3D array can be assigned to selected molecules, allowing for synthesis and retrieval from those locations. The supports may include aperture walls in stacked plates, be suspended within stacked plate apertures, or be contained in porous enclosures. A support transfer device is also described, which enables the transfer of solid-phase supports used in a 3D array.
Career Highlights
Stephen A. Baum has worked with prominent companies in the pharmaceutical and biotechnology sectors, including Aventis Pharmaceuticals Inc. and Selectide Corporation. His experience in these organizations has contributed to his expertise in chemical synthesis and innovation.
Collaborations
Throughout his career, Baum has collaborated with notable individuals such as Marcel Patek and Safar Pavel. These collaborations have likely enriched his work and expanded the impact of his inventions.
Conclusion
Stephen A. Baum's innovative contributions to the field of chemical synthesis have paved the way for advancements in combinatorial libraries and molecular synthesis techniques. His patents reflect a deep understanding of the complexities involved in chemical composition tracking and parallel synthesis methodologies.