Stephan S Rothman

Title: Innovations by Stephan S Rothman

Introduction

Stephan S Rothman is a notable inventor based in Berkeley, CA. He has made significant contributions to the field of biotechnology, particularly in the area of nucleic acid transfection. With a total of 2 patents to his name, Rothman's work has the potential to impact gene therapy and molecular biology.

Latest Patents

Rothman's latest patent is titled "Method for nucleic acid transfection of cells." This invention describes methods for introducing nucleic acids into a target cell using a transition metal enhancer. A mixture containing nucleic acid and a transition metal enhancer is exposed to cells. The nucleic acid is taken up into the interior of the cell with the aid of the transition metal enhancer. Since nucleic acids can encode a gene, the method can be used to replace a missing or defective gene in the cell. The method can also be used to deliver exogenous nucleic acids operatively coding for proteins that are secreted or released from target cells, thus resulting in a desired biological effect outside the cell. Alternatively, the methods of the present invention can be used to deliver exogenous nucleic acids into a target cell that are capable of regulating the expression of a predetermined endogenous gene. This can be accomplished by encoding the predetermined endogenous gene on the nucleic acid or by encoding the nucleic acid with a sequence that is the Watson-Crick complement of the mRNA corresponding to the endogenous gene.

Career Highlights

Rothman is currently associated with Genteric, Inc., where he continues to innovate in the field of genetic engineering. His work is pivotal in advancing techniques that could lead to breakthroughs in medical treatments and therapies.

Collaborations

Some of his notable coworkers include Michael J Bennett and Michael H Nantz, who contribute to the collaborative efforts at Genteric, Inc. Their combined expertise enhances the research and development initiatives within the company.

Conclusion

Stephan S Rothman is a prominent figure in biotechnology, with innovative patents that hold promise for future advancements in gene therapy. His contributions are shaping the landscape of molecular biology and genetic engineering.