Stefan G. Koenig is a notable inventor based in Shrewsbury, MA (US). He has made significant contributions to the field of chemistry, particularly in the preparation of chiral compounds. With a total of four patents to his name, his work has implications for various applications in pharmaceuticals.

Latest Patents

One of his latest patents focuses on the "Preparation of chiral amides and amines." This invention provides a convenient method for converting oximes into enamides. The process does not require the use of metallic reagents, thereby producing the desired compounds without generating a large volume of metallic waste. The enamides serve as useful precursors to amides and amines. The invention also outlines a process to convert a prochiral enamide into the corresponding chiral amide. In an exemplary process, a chiral amino center is introduced during hydrogenation through the use of a chiral hydrogenation catalyst. Selected embodiments of the invention provide methods of preparing amides and amines that include the 1,2,3,4-tetrahydro-N-alkyl-1-naphthalenamine or 1,2,3,4-tetrahydro-1-naphthalenamine substructure.

Career Highlights

Stefan G. Koenig is currently associated with Sunovion Pharmaceuticals Inc., where he continues to innovate in the field of pharmaceutical chemistry. His work has been instrumental in advancing methods for synthesizing important chemical compounds.

Collaborations

Some of his notable coworkers include Surendra Singh and Roger P. Bakale, who have collaborated with him on various projects within the pharmaceutical sector.

Conclusion

Stefan G. Koenig's contributions to the field of chemistry, particularly in the preparation of chiral amides and amines, highlight his innovative spirit and dedication to advancing pharmaceutical science. His work continues to influence the development of new compounds that are essential in various applications.

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