Stefan Arnold

Title: Contributions of Inventor Stefan Arnold in Recombinant Hormone Purification

Introduction

Stefan Arnold is an innovative inventor based in Schwetzingen, Germany. He has made significant contributions to the field of biotechnology, particularly in the area of recombinant hormone purification. Over the course of his career, he has been awarded three patents, showcasing his expertise in the creation of methodologies and tools that aid in medical treatments.

Latest Patents

One of Stefan's latest patents is titled "Method for Purifying Recombinant FSH". This invention pertains to a unique purification method for a recombinant follicle stimulating hormone (FSH) or its variants. The process involves subjecting a liquid that contains recombinant FSH to anion exchange chromatography, hydrophobic interaction chromatography, and dye affinity chromatography. Importantly, this method does not include weak anion exchange chromatography or reverse phase chromatography. The purification process results in a high yield of recombinant FSH with the desired purity level, which is particularly useful for treating disorders where FSH preparations are needed.

Another significant patent is related to "FSH Producing Cell Clone". This invention includes nucleic acid molecules that encode the alpha and beta chains of human FSH, modified for optimized codon usage in Chinese Hamster Ovary (CHO) cells. Additionally, it covers recombinant nucleic acid molecules and host cells containing those sequences. The invention also presents a method for producing host cells that express human FSH by transfecting cells in suspension culture under serum-free conditions with the recombinant nucleic acid.

Career Highlights

Throughout his career, Stefan Arnold has collaborated with notable companies such as Ratiopharm GmbH and Biogenerix AG. His work has contributed to advancements in the biotechnology sector, providing technologies crucial for hormone production and purification.

Collaborations

Stefan has worked alongside notable colleagues Christian Scheckermann and Dietmar Eichinger. Their combined expertise in the field has facilitated the development of innovative solutions that enhance the efficiency and efficacy of recombinant hormone processes.

Conclusion

In summary, Stefan Arnold stands out as a pivotal inventor in the field of biotechnology. His contributions through his patents, particularly in the area of recombinant FSH purification, highlight his commitment to advancing medical treatments. His collaborations and the companies he has worked for further reflect his professional impact and ongoing relevance in the innovation landscape.