Song S Er

Title: The Innovative Contributions of Song S Er

Introduction

Song S Er is a notable inventor based in Scarborough, Canada. He has made significant contributions to the field of biomedical engineering, particularly in the development of blood substitutes. His innovative approach to modifying hemoglobin has the potential to impact medical practices significantly.

Latest Patents

Song S Er holds a patent for "Selective crosslinking of hemoglobin by oxidized, ring-opened saccharides." This invention involves modifying hemoglobin to form the basis of a blood substitute. The process includes crosslinking hemoglobin through a reaction with a polyaldehyde produced by the ring-opening oxidation of di/tri-saccharides, such as raffinose. The reaction is carefully controlled at a pH of about 5.0-7.0 and a stoichiometry of approximately 1:1-4:1 based on the molar ratio of di/tri-saccharide to hemoglobin tetramers. This meticulous approach ensures the consistent production of polyaldehyde without unwanted side products, leading to high yields of stabilized, tetrameric hemoglobin and oligomers with beneficial properties.

Career Highlights

Song S Er is associated with Hemosol Inc., a company focused on developing innovative blood products. His work has contributed to advancements in the field, particularly in creating safer and more effective blood substitutes.

Collaborations

He has collaborated with notable colleagues, including Diana H Pliura and Lawrence T Wong, who have also contributed to the research and development of blood substitute technologies.

Conclusion

Song S Er's innovative work in modifying hemoglobin represents a significant advancement in biomedical engineering. His contributions have the potential to enhance medical treatments and improve patient outcomes.