Song Gao

Title: Innovations of Song Gao in Genetic Engineering

Introduction

Song Gao is a prominent inventor based in Wuxi, China. He has made significant contributions to the field of genetic engineering and bioengineering. His innovative work focuses on the synthesis of carminic acid, which has applications in various industries.

Latest Patents

Song Gao holds a patent titled "Construction of recombinant for synthesizing carminic acid and application thereof." This patent discloses the construction of recombinant Saccharomyces cerevisiae for synthesizing carminic acid. The invention involves the heterologous expression of several key enzymes, including cyclase Zhul, aromatase ZhuJ, OKS of Octaketide synthase 1, C-glucosyltransferase UGT2, monooxygenase aptC, and 4'-phosphopantetheinyl transferase npgA. The recombinant organism can synthesize carminic acid using self-synthesized acetyl-CoA and malonyl-CoA as precursors. By integrating relevant enzymes into a high copy site, the yield of carminic acid can be significantly improved, reaching up to 2664.6 µg/L under optimized fermentation conditions.

Career Highlights

Song Gao is affiliated with Jiangnan University, where he conducts his research and development activities. His work has been instrumental in advancing the production of carminic acid, which is valuable in the cosmetics, textiles, and food industries. His innovative approaches have garnered attention in the scientific community.

Collaborations

Song Gao has collaborated with notable colleagues, including Jingwen Zhou and Qian Zhang. Their combined efforts contribute to the ongoing research and development in the field of genetic engineering.

Conclusion

Song Gao's contributions to the synthesis of carminic acid through genetic engineering highlight his innovative spirit and dedication to advancing science. His work not only enhances production efficiency but also opens new avenues for applications in various industries.