Company Filing History:
Years Active: 2017
Title: Sofia A Casares: Innovator in Vaccine Development
Introduction
Sofia A Casares is a prominent inventor based in Potomac, MD (US). She has made significant contributions to the field of immunology, particularly in vaccine development. With a total of 2 patents, her work focuses on innovative approaches to enhance immune responses against pathogens.
Latest Patents
One of her latest patents is related to TH1/TH2 polarizing vaccines. This invention involves recombinant chimeric molecules that facilitate T cell receptor interaction and costimulation for the activation and differentiation of pathogen-specific T cells toward effector T helper 1 (Th1) or T helper 2 (Th2) cells. The chimera is designed to elicit antibodies against pathogen-specific B cell epitopes. Additionally, the invention includes methods for utilizing these chimeric molecules in whole or as components of a vaccine.
Another significant patent is the development of a humanized transgenic mouse model. This model is crucial for testing the immunogenicity and protective efficacy of human vaccines. It provides a method for generating a multitransgenic animal capable of expressing human leukocyte antigen DR4 and human costimulatory molecules (CD80) upon infusion of human HLA-matched hematopoietic stem cells. This model can develop a functional human immune system, making it invaluable for vaccine research.
Career Highlights
Sofia A Casares works at the USA as represented by the Secretary of the Navy. Her role involves pioneering research that bridges the gap between basic science and practical applications in vaccine development. Her innovative work has the potential to significantly impact public health.
Collaborations
Sofia collaborates with esteemed colleagues such as Thomas L Richie and Teodor D Brumeanu. These partnerships enhance her research capabilities and contribute to the advancement of immunological studies.
Conclusion
Sofia A Casares is a trailblazer in the field of vaccine innovation, with her patents reflecting her commitment to improving human health through advanced immunological research. Her contributions are poised to make a lasting impact on vaccine development and public health initiatives.