This inventor holds 1 USPTO granted patent and 1 EPO patent. Top assignee: Other. Active years: 2017.
Company Filing History:
1 out of 834,453 Years Active: 2017
Title: Siyuan Gao: Innovator in Pharmaceutical Crystallization
Introduction
Siyuan Gao is a notable inventor based in Shanghai, China. He has made significant contributions to the field of pharmaceutical sciences, particularly in the development of stable crystalline forms of drugs. His work focuses on improving the stability and usability of pharmaceutical compounds.
Latest Patents
Siyuan Gao holds a patent for a "Stable apremilast crystalline form II free of solvate and method of making the same." This invention discloses a stable crystalline Form II of non-solvate of Apremilast, along with methods for its production. The patent also covers pharmaceutical compositions that include Form II and their various applications. The crystalline forms are characterized using advanced techniques such as X-ray powder diffractometry (XRPD), infrared spectroscopy (IR), differential scanning calorimetry (DSC), and thermal gravimetric analysis (TG). Compared to previously reported forms, Apremilast Form II is more stable under temperature, light, and humidity conditions, making it suitable for long-term storage. The crystallization solvents used are safe and easily removable, and the Form II has a white or off-white appearance, allowing for direct use in preparation processing. The methods of preparation are simple, reproducible, and suitable for industrial production.
Career Highlights
Throughout his career, Siyuan Gao has worked with various companies, including Utopharm Co., Ltd. His expertise in pharmaceutical crystallization has positioned him as a valuable asset in the industry.
Collaborations
Siyuan Gao has collaborated with notable colleagues such as Junzhi Luo and Jing Nian. Their combined efforts have contributed to advancements in the field of pharmaceutical sciences.
Conclusion
Siyuan Gao's innovative work in the development of stable crystalline forms of pharmaceuticals highlights his significant impact on the industry. His contributions are paving the way for improved drug formulations and stability.