Siyi Zhou

Title: Siyi Zhou and Fish Swim Bladder-Derived Heparin-Like Mucopolysaccharide

Introduction

Siyi Zhou is an inventor associated with Zhanjiang City, China, and has one patent listed in the provided information. Her work concerns a fish swim bladder-derived heparin-like mucopolysaccharide and its potential use in inhibiting angiogenesis.

Latest Patents

The patent, “Fish Swim Bladder-Derived Heparin-Like Mucopolysaccharide and Methods of Making and Using the Same,” describes an application of the substance in preparing angiogenesis inhibitors. It identifies the structural unit as α-ΔGlcUA-[1→3]-GalNAc-4S and reports strong inhibition of angiogenesis. In the examples, a concentration of 400 mg/L inhibited the growth of human umbilical vein endothelial cells by up to 90.3%, while 1 mg/mL inhibited angiogenesis in the chick embryo chorioallantoic membrane by 77.15%.

Career Highlights

The provided information associates Zhou with Guangdong Ocean University and the Shenzhen Institute of Guangdong Ocean University. Her listed patent highlights research into a marine-derived compound with potential relevance to medication development.

Collaborations

Zhou’s listed coworkers include Saiyi Zhong and Jing Chen. Their names are provided as collaborators, though specific roles in the patent work are not stated.

Conclusion

Siyi Zhou’s listed invention explores the anti-angiogenic potential of a fish swim bladder-derived mucopolysaccharide, connecting research associated with Guangdong Ocean University to a possible pharmaceutical application.