This inventor holds 1 USPTO granted patent and 1 EPO patent. Top assignees: Charité – Universitätsmedizin Berlin, Max-Delbrück-Centrum Für Molekulare Medizin in Der. Active years: 2025.
Company Filing History:
1 out of 283 
1 out of 2 Years Active: 2025
Title: Simone Rhein: Innovator in Immunotherapy
Introduction
Simone Rhein is a prominent inventor based in Berlin, Germany. She has made significant contributions to the field of immunotherapy, particularly in the development of T cell therapies for cancer treatment. Her innovative work focuses on addressing B cell malignancies, which are critical areas in cancer research.
Latest Patents
Simone Rhein holds a patent for "CD22-specific T cell receptors and adoptive T cell therapy for treatment of B cell malignancies." This invention is directed towards the field of immunotherapy, specifically adoptive T cell therapy or T cell receptor (TCR) gene therapy for cancer. The patent provides a nucleic acid encoding TCR alpha or beta chain constructs capable of specifically binding to a peptide derived from the lineage-specific antigen CD22. This technology aims to lyse CD22-positive cells, offering therapeutic potential for conditions such as diffuse large B-cell lymphoma (DLBCL).
Career Highlights
Throughout her career, Simone has worked with esteemed institutions such as Charité – Universitätsmedizin Berlin and Max-Delbrück-Centrum für Molekulare Medizin. Her research has been pivotal in advancing the understanding and treatment of B cell malignancies through innovative therapeutic approaches.
Collaborations
Simone has collaborated with notable colleagues, including Thomas Blankenstein and Antonio Pezzutto. These partnerships have enriched her research and contributed to the development of groundbreaking therapies in the field of immunotherapy.
Conclusion
Simone Rhein's contributions to immunotherapy exemplify the impact of innovative research in the fight against cancer. Her work continues to inspire advancements in the treatment of B cell malignancies, showcasing the importance of collaboration and innovation in medical science.