Title: Simon Messner - Innovator in Liver Disease Research
Introduction: Simon Messner is an accomplished inventor based in Zürich, Switzerland. He is currently associated with Insphero AG, a company that specializes in advanced 3D cell culture technology. Although he has not yet been granted any patents, his work focuses on developing innovative solutions for studying liver diseases.
Latest Patent Applications: Simon Messner has been involved in several significant patent applications. One of his latest applications is titled "Screenable Liver Disease Models and Methods." This application describes an in vitro testing platform designed for the study of metabolic liver disease and related therapeutic strategies. The platform comprises an artificial spheroidal microtissue that includes hepatocytes, hepatic stellate cells, and various types of hepatic inflammatory cells. It also incorporates medium and reagents capable of simulating different stages of metabolic liver disease and their progression, allowing for the testing of preventive and therapeutic strategies through pharmacological and dietary interventions.
Another notable application is "3D Tissue Culture Materials and Processes for Producing Same." This application focuses on a 3D tissue culture that can be hydrogel-based or cellular self-assembly. It also outlines a method for preparing cells for 3D tissue culture, which involves plating the cells on a suitable surface, checking their adherence, discarding non-adhered cells, and transferring the adhered cells into a 3D tissue culture process.
Conclusion: Simon Messner is a dedicated inventor making strides in the field of liver disease research through his innovative patent applications. His work at Insphero AG highlights the importance of developing advanced models for studying complex diseases.