Company Filing History:
Years Active: 2020
Title: Simon J Elsasser: Innovator in Unnatural Amino Acid Incorporation
Introduction
Simon J Elsasser is a notable inventor based in Cambridge, GB. He has made significant contributions to the field of protein engineering, particularly in the incorporation of unnatural amino acids into proteins. His innovative work has implications for various applications in biotechnology and pharmaceuticals.
Latest Patents
Simon J Elsasser holds a patent titled "Use of eRF1 mutants in unnatural amino acid incorporation." This invention relates to a method for incorporating an unnatural amino acid into a protein of interest within a eukaryotic cell. The method involves providing a eukaryotic cell that expresses an orthogonal tRNA synthetase-tRNA pair, a nucleic acid sequence encoding the protein of interest, and a mutant eRF1. The mutant eRF1 has an amino acid sequence with at least 60% sequence identity to the human wild type eRF1 sequence. The process includes incubating the eukaryotic cell in the presence of the unnatural amino acid, allowing for its incorporation into the protein via the orthogonal tRNA synthetase-tRNA pair. This patent represents a significant advancement in the field of synthetic biology.
Career Highlights
Simon J Elsasser is affiliated with United Kingdom Research and Innovation, where he continues to explore innovative methods in protein synthesis. His work has garnered attention for its potential to revolutionize how proteins are engineered for various applications.
Collaborations
Simon has collaborated with esteemed colleagues such as Jason W Chin and Wolfgang H Schmied. These collaborations have further enhanced the impact of his research and innovations in the field.
Conclusion
Simon J Elsasser is a pioneering inventor whose work in unnatural amino acid incorporation is paving the way for advancements in biotechnology. His contributions are vital for the future of protein engineering and synthetic biology.