Company Filing History:
3 out of 937 
2 out of 340 
Years Active: 1997-2002
Title: The Innovations of Simon A. Sherman
Introduction
Simon A. Sherman is a notable inventor based in Omaha, Nebraska. He has made significant contributions to the field of biochemistry, particularly through his innovative patents. With a total of three patents to his name, Sherman has focused on developing high-affinity response-selective C-terminal analogs of C5 and C5a anaphylatoxin.
Latest Patents
Sherman's latest patents include high-affinity response-selective C-terminal analogs of C5a anaphylatoxin. These analogs possess a constrained backbone conformation at the C-terminus, which enhances their potency. The specific β-turn motif in these compounds allows for selective elicitation of biological responses associated with C5a. Exemplary compounds include decapeptide analogs with the formula: A1-Ser-Phe-Lys-A2-A3-A4-A5-A6-A7, where the constrained β-turn is localized in the region of A4-A7.
Career Highlights
Throughout his career, Simon A. Sherman has worked with prestigious institutions such as the University of Nebraska and the University of Queensland. His research has contributed to advancements in understanding the biological roles of anaphylatoxins and their analogs.
Collaborations
Some of Sherman's notable coworkers include Sam D. Sanderson and Leonid Kirnarsky. Their collaborative efforts have furthered the research and development of innovative biopharmaceuticals.
Conclusion
Simon A. Sherman is a distinguished inventor whose work in developing high-affinity response-selective C-terminal analogs has made a significant impact in the field of biochemistry. His contributions continue to influence research and innovation in this area.