Company Filing History:
Years Active: 2011
Title: **Innovative Contributions of Silvio Ernesto Perea Rodriquez in the Field of Molecular Pharmacology**
Introduction
Silvio Ernesto Perea Rodriquez, an inventor based in Ciudad de la Habana, CU, has made significant strides in the field of molecular pharmacology. His contributions focus on developing novel peptides aimed at treating cancer associated with the human papilloma virus (HPV) and other epithelial tumors. His groundbreaking work exemplifies the critical intersection of molecular biology and oncology.
Latest Patents
Rodriquez holds a patent for his invention titled "Peptides for the treatment of cancer associated with the human papilloma virus (HPV) and other epithelial tumors." This innovative solution targets the Casein Kinase II (CKII) phosphorylation domain, providing a method to inhibit its activity. The patent showcases eleven unique cyclic peptides that not only block CKII phosphorylation in vitro but also exhibit cytotoxic effects on HPV-16 transformed cells, specifically the CaSki cell line. Additionally, these peptides have been shown to enhance the sensitivity of these cells to the cytostatic effects of interferon (IFN).
Career Highlights
Working at the renowned Centro de Ingeniería Genética y Biotecnología, Rodriquez has made noteworthy contributions to the development of therapies aimed at combating HPV-related epithelial tumors. His research emphasizes the importance of identifying peptides that can effectively disrupt cancerous processes, thereby paving the way for new therapeutic avenues in oncology.
Collaborations
Silvio Ernesto Perea Rodriquez has collaborated with esteemed colleagues such as Osvaldo Reyes Acosta and Nelson Francisco Santiago Vispo. This teamwork highlights the collaborative spirit present in research institutions, where shared knowledge and expertise are crucial for achieving innovative outcomes.
Conclusion
The work of Silvio Ernesto Perea Rodriquez represents a vital advancement in the field of cancer research and treatment. His innovative peptides hold promise for enhancing the efficacy of therapies against HPV-related cancers, potentially improving outcomes for patients. As research continues to evolve, Rodriquez's contributions remain an essential part of the scientific dialogue surrounding molecular pharmacology and oncology.