Sidney Pehrson

Title: Sidney Pehrson’s Patent on pH Probe Calibration Verification.

Introduction

Sidney Pehrson is an inventor associated with Belmont, Massachusetts, and Amgen Inc. Her work includes a patented process for verifying the calibration status of pH probes during low-pH viral inactivation.

Latest Patents

Pehrson is credited with 1 patent, titled “In-process verification of calibration status of pH probes.” The invention describes an automated process for treating an elution pool to reduce viral concentration while checking pH probe calibration during production.

The process moves the pool through vessels as its pH is measured, adjusted, and held for a period sufficient for viral inactivation. While the pool is being processed, vessels are filled with buffers of known pH, and the buffer readings are compared with the probes’ measurements to determine whether recalibration is needed. This approach integrates calibration checks into the production workflow.

Career Highlights

Pehrson’s patent addresses process monitoring in biopharmaceutical manufacturing. By incorporating probe verification into the viral-inactivation sequence, the method is designed to help identify calibration issues during processing.

Collaborations

The supplied information lists Venkatesh Natarajan and Marco DeLiso as Pehrson’s coworkers. The patent is associated with Amgen Inc.

Conclusion

Sidney Pehrson’s patented method combines low-pH viral inactivation with in-process pH probe calibration checks, reflecting an innovation focused on monitoring reliability in biopharmaceutical manufacturing.